Updated to include the newest drugs and those currently in
development, this Fourth Edition is a comprehensive reference on the
preclinical and clinical pharmacology of anticancer agents. Organized
by drug class, the book provides the latest information on all drugs
and biological agents뾲heir mechanisms of action, interactions with
other agents, toxicities, side effects, and mechanisms of resistance.
The authors explain the rationale for use of drugs in specific
schedules and combinations and offer guidelines for dose adjustment
in particular situations. This edition provides expanded coverage of
monoclonal antibodies, molecularly targeted drugs, vaccines, cell
based therapies, growth factors, and pharmacogenetics.