Percutaneous Absoprtion:Drugs Cosmetics Mechanisms Met

(Drugs & the Pharmaceutical Sc),4/e

1 Mathematical models in percutaneous absorption by Michael S. Roberts and Yuri
G. Anissimov 1
2 Skin metabolism during in vitro percutaneous absorption by Robert L. Bronaugh
and Margaret E. K. Kraeling and Jeffrey J. Yourick 45
3 Cutaneous metabolism of xenobiotics by Saqib J. Bashir and Howard I. Maibach
51
4 Occlusion does not uniformly enhance penetration in vivo by Daniel Bucks and
Howard I. Maibach 65
5 Regional variation in percutaneous absorption : principles and applications
to human risk assessment by Ronald C. Wester and Howard I. Maibach 85
6 In vivo relationship between percutaneous absorption and transepidermal water
loss by Andrew Rougier and Claire Lotte and Howard I. Maibach 95
7 Skin contamination and absorption of chemicals from water and soil by Ronald
C. Wester and Howard I. Maibach 107
8 In vivo percutaneous absorption : a key role for stratum corneum/vechicle
partitioning by Andrew Rougier 123
9 Protein allergens : skin as a route of exposure by Camilla K. Pease and David
A. Basketter and Ian R. White 139
10 Percutaneous absorption of chemical mixtures by Jim E. Riviere 155
11 Does desquamation reduce permeation? by Micaela B. Reddy and Annette L.
Bunge 165
12 Penetration and distribution in human skin focusing on the hair follicle by
Ylva Grams and Joke Bouwstra 177
13 Evaluation of stratum corneum heterogeneity by Gerald B. Kasting and Matthew
A. Miller and Priya S. Talreja 193
14 The skin reservoir for topically applied solutes by Michael S. Roberts and
Sheree E. Cross and Yuri G. Anissimov 213
15 Effects of occlusion : percutaneous absorption by Hongbo Zhai and Howard I.
Maibach 235
16 Variations of hair follicle size and distribution in different body sites by
Nina Otberg and Heike Richter and Hans Schaefer and Ulrike Blume-Peytavi and
Wolfram Sterry and Jurgen Lademann 247

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