Cognitive Neuroscience of Aging:Linking Cognitive and Cerebral Aging

Description
Until very recently, what we knew about the neural basis of cognitive
ageing was based on two disciplines that had very little contact with
each other. Whereas the neuroscience of ageing investigated the
effects of aging on the brain independently of age-related changes in
cognition, the cognitive psychology of ageing investigated the
effects of ageing on cognition independently of age related changes
in the brain. Because an increasing number of studies have focused on
the relationships between cognitive ageing and cerebral ageing, these
two disciplines have begun to interact. This rapidly growing body of
research has come to constitute a new discipline: cognitive
neuroscience of ageing.

The goal of this book is to introduce this new discipline at a level
that is useful to both professionals and students in cognitive
neuroscience, cognitive psychology, neuroscience, neuropsychology,
neurology, and related areas. The book is divided into four main
sections. The first section describes non-invasive measures of
cerebral ageing, including structural (e.g. volumetric MRI),
chemical, (e.g. dopamine PET), electrophysiological (e.g. ERP's), and
hemodynamic measures (e.g. fMRI), and discusses how they can be
linked to behavioural measures of cognitive ageing. The second
section reviews evidence for the effects of ageing on neural activity
during different cognitive functions, including perception and
attention, use of imagery, working memory, long-term memory, and
prospective memory. The third section focuses on clinical and applied
concerns, such as the distinction between health ageing and ageing
with Alzheimer's disease, and the use of cognitive training to
ameliorate age-related cognitive decline. The final section describes
theories that relate cognitive and cerebral ageing, including models
accounting for functional neuroimaging evidence and models supported
by computer simulations. Taken together, the chapters in this volume
provide the first unified and comprehensive overview of the new
discipline of cognitive neuroscience of ageing.



- Contents-


Introduction
1 Roberto Cabeza, Lars Nyberg & Denise C. Park: Cognitive
neuroscience of ageing: emergence of a new discipline
Part 1: Imaging measures
2 Naftali Raz: The ageing brain observed in vivo: differential
changes and their modifiers
3 Lars Backman & Lars Farde: The role of dopamine receptors in
cognitive ageing
4 Monica Fabiani & Gabriele Gratton: Electrophysiological and optical
measures of cognitive ageing
5 Adam H. Gazzaley & Mark D'Esposito: Functional MRI and cognitive
ageing
6 Michael D. Rugg & Alexa M. Morcom: The relationship between brain
activity, cognitive performance and ageing: the case of memory
Part 2: Basic cognitive processes
7 David J. Madden, Wythe L. Whiting & Scott A. Huettel: Age-related
changes in neural activity during visual perception and attention
8 Patricia A. Reuter-Lorenz & Ching-Yune C. Sylvester: The cognitive
neuroscience of working memory and agting
9 Denise A. Park & Angela G. Gutchess: Long-term memory and ageing: a
cognitive neuroscience perspective
10 Robert West: The neural basis of age-related declines in
prospective memory
Part 3: Clinical and applied issues
11 Iandy L. Buckner: Three principles for cognitive ageing research:
multiple causes sequelae, variance in expression and response, and
the need for integrative theory
12 Cheryl L. Grady: Functional connectivity during memory tasks in
healthy ageing and dementia
13 Lars Nyberg: Cognitive training in health ageing: a cognitive
neuroscience perspective
Part 4: Models in cognitive neuroscience of ageing
14 Sander Daselaar & Roberto Cabeza: Age-related changes in
hemospheric organization
15 Shu-Chen Li: Neurocomputational perspectives linking
neuromodulation, processing noise, representational distinctiveness,
and cognitive ageing





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