Endocrinology 5/e 3-Volume Set

hardcover - 4320 pages. 1450 illustrations. 5th edition.

Revised throughout, the 5th Edition of this leading reference presents a
complete and up-to-date review and analysis of all aspects of endocrinology,
diabetes, and bone metabolism. Readers will also find state-of-the-art
information on genetics, proteinomics, and hormone signaling, and coverage of
the field뭩 hottest topics in nearly 20 new chapters. Joined by an
international team of leading experts뾪any new to this edition뾆rs. Jameson
and DeGroot provide guidance that integrates the basic science of endocrinology
with clinical medicine and the practical management of endocrine disorders. A
clinical focus emphasizes diagnosis and therapy.

Key Features

* Features the work of the world뭩 leading authorities뾪any new to this
edition.
* Organizes information into basic and clinical sections that makes reference
quick and easy.
* Provides tables designed to summarize and organize information, and presents
over 1,400 illustrations that clarify complex concepts.



New to this Edition

* Examines the hottest topics in the field today through 19 new chapters
including Endocrinology: Impact on science and medicine ?Application of
genomics and proteinomics to endocrinology ?Genetic syndromes in
endocrinology ?Genetics and syndromes of obesity ?Role of the adipocyte in
metabolism and endocrine function ?Genetic Defects and Disorders of Bone ?
and Adrenal causes of hypercortisolism.

* Features many new authors, offering fresh perspectives.
















I. PRINCIPLES OF HORMONE ACTION
1. Endocrinology: Impact on science and medicine
II. GENOMICS & ENDOCRINOLOGY
2. Hormones and gene expression: basic principles 3. Cell division,
differentiation, senescence, and death 4. Appication of genomics and
proteinomics to endocrinology 5. Transgenic and genetic animal models 6.
Genetic syndromes in endocrinology
III. MECHANISMS OF ENDOCRINE SIGNALING & RESPONSE
7. Control of hormone secretion 8. Hormone signaling via tyrosine kinase
receptors 9. Hormone signaling via cytokine receptors 10. Hormone signaling via
serine kinase receptors 11. Hormone signaling via G-protein coupled receptors
12. Cyclic AMP signaling pathway 13. Second messenger signaling pathways:
Phospholipids and calcium 14. MAP kinase and growth factor signaling pathways
15. Nuclear receptors: Sturcture, function and co-factors
IV. NEUROENDOCRINOLOGY & PITUITARY DISEASE
16. Development of the pituitary 17. Prolactin 18. ACTH 19. Endocrine rhythms
and the clock 20. Hypothalamic syndromes 21. Evaluation of hypothalamic and
pituitary masses 22. Hypopituitarism 23. Acromegaly 24. Cushing뭩 Disease and
Syndrome 25. Non-functioning ademonas and gonadotrophinomas 26. TSH-producing
adenomas 27. Prolactinoma 28. Pituitary surgery 29. Evaluation and management
of childhood hypothalamic and pituitary tumors 30. Posterior pituitary,
diabetes insipidus, SIADH 31. The pineal gland: basic physiology and clinical
implications
V. GROWTH & MATURATION
32. Growth hormone 33. Regulation of GH secretion 34. ICH-I, IGF-BPs, and IFG-
II 35. Other growth factors 36. Growth and maturation 37. Growth hormone
deficiency in children 38. Growth hormone deficiency in adults
VI. IMMUNOLOGY & ENDOCRINOLOGY
39. Autoimmune endocrine disease 40. Interactions of the Endocrine and Immune
Systems 41. Autoimmune polyglandular failure syndromes
VII. OBESITY, ANOREXIA, AND NUTRITION
42. Appetite regulation and thermogenesis 43. Obesity: The problem and its
management 44. Genetics and syndromes of obesity ( 45. Anorexia Nervosa,
Bulimia Nervosa, and other eating disorders 46. Starvation and parenteral
VIII. DIABETES MELLITUS
47. Development of the endocrine pancreas 48. Chemistry and biosynthesis of the
islet hormones 49. Secretion and metabolism of insulin 50. Insulin action 51.
Glucagon and the glucagon-like peptides 52.