Inflammatory Diseases of Blood Vessels

Preface
Contributors
I Scientific Basis for Health and Disease
1 Vasculitis: A Dialogue Between the Artery and the Immune System 1
2 Endothelial Cell Adhesion Molecules 13
3 Extracelluar Matrix 29
4 Autoantibodies in Vasculitis 37
5 T Cells in Vascular Disease 57
6 Neutrophils in Vasculitis 69
7 Oxygen Metabolites and Vascular Damage 83
8 Cytokines and Vascular Inflammation 97
9 Fc Receptors in Vascular Diseases 113
10 Pathophysiology of Atherothrombosis: Role of Inflammation 127
11 Infectious Aspects of Atherosclerosis 141
12 Cellular Immune Responses in Atherosclerosis 155
13 Cooperative Molecular Interactions in the Regulation of Angiogenesis 175
14 Animal Models of Vasculitis 193
II Primary Vasculitides
15 Historical Perspectives 209
16 Epidemiology of Vasculitis 225
17 General Approach to the Diagnosis of Vasculitis 239
18 Histopathology of Primary Vasculitic Disorders 255
19 Noninvasive Radiographic Approach to Differential Diagnosis of the
Vasculitides 267
20 Angiography of Vasculitis 279
21 Kawasaki Disease 305
22 Henoch-Schonlein Purpurn 321
23 Microscopic Polyangiitis: Pathogenesis 339
24 Microscopic Polyangiitis: Clinical Aspects 355
25 Wegener's Granulomatosis: Pathogenesis 365
26 Wegener's Granulomatosis: Clinical Aspects 381
27 Churg-Strauss Syndrome: Clinical Aspects 399
28 Giant Cell Arteritis: Pathogenesis 413
29 Giant Cell Arteritis: Clinical Aspects 425
30 Takayasu's Arteritis: Pathogenesis 443
31 Takayasu's Arteritis: Clinical Aspects 455
32 Takayasu's Arteritis: Surgical Treatment 467
33 Behcet's Disease 473
34 Cogan's Syndrome 491
35 Vasculitis of the Central Nervous System 511
36 Cutaneous Vasculitis and Its Relationship to Systemic Disease 529
37 Thromboangiitis Obliterans (Buerger's Disease) 539
III Secondary Vasculitides
38 Virus-Associated Vasculitides: Pathogenesis 553
39 Virus-Associated Vasculitides: Clinical Aspects 565
40 Vasculitis Secondary to Bacterial, Fungal, and Parasitic Infection 599
41 Vasculitis and Rheumatoid Arthritis 609
42 Systemic Sclerosis with Vascular Emphasis 619
43 Sjogren's Syndrome 637
44 Vasculitis in Systemic Lupus Erythematosus 649
45 Vasculitis in the Idiopathic Inflammatory Myopathies 665
46 Relapsing Polychondritis 675
47 Systemic Vasculitis in Sarcoidosis 695
48 Vasculitis and Malignancy 707
49 Drug-Induced Vasculitis 727
50 Inflammatory Aspects of Acute Coronary Syndromes 747
51 Dyslipidemia in Rheumatic Disorders 767
52 Considerations for Novel Therapies in the Future 781
Index 799