A collection of cutting-edge techniques for studying ubiquitin-dependent
protein degradation via the proteasome. The topics covered range broadly from
basic biochemistry to cellular assays to discovery techniques using mass
spectrometric analysis. These biochemical and cellular methods are necessary to
explore the ubiquitin뻪roteasome system and ubiquitin뻪roteasome-dependent
functions. State-of-the-art and user-friendly, Ubiquitin뻇roteasome Protocols
offers novice and experienced bench scientists alike a thorough compendium of
readily reproducible techniques that will accelerate discovery, enhance
productivity, and permit manipulation of the system for varied research
purposes.