The third edition of this textbook ?which is based on the traditional philosophies of Bourn Hall뭩 comprehensive
training program - expands and updates the second edition, published in 1999. The content is comprehensive, covering
the assessment of infertile couples and the laboratory and clinical aspects of their treatment by assisted
reproductive
technologies. The emphasis throughout is on the practical management of patients undergoing assisted conception
treatment. This textbook is an essential work of reference for all clinicians and scientists working in reproductive
medicine. Included with this edition are many of the Bourn Hall Procedures, Protocols and Information Sheets, which
have been formatted on CD-ROM, to enable readers to customize them for their own use.
Table of Contents
Preface
An introduction to Bourn Hall : the biomedical background of Bourn Hall clinic 1
The Bourn Hall story continues 9
Patient selection and management 15
The management of infertile men presenting in the assisted conception unit 35
Laboratory investigation of the infertile male 61
Ultrasound in assisted conception 93
Diagnostic hysteroscopy in assisted conception 107
Historical perspectives in the management of fertility and the use of gonadotropins 129
Superovulation for assisted conception : the new gonadotropins 153
The use of gonadotropin releasing hormone agonists and antagonists in infertility 165
Superovulation strategies in assisted conception 177
Polycystic ovaries and their relevance to assisted conception 189
Classification, pathophysiology and management of ovarian hyperstimulation syndrome 217
Intrauterine insemination 259
Oocyte recovery and embryo transfer techniques for in vitro fertilization 271
Routine gamete handling : oocyte collection and embryo culture 287
Laboratory techniques : sperm preparation for assisted conception 309
Cryopreservation of embryos and spermatozoa 319
Assisted reproduction techniques for male-factor infertility : current status of intracytoplasmic sperm injection 337
Alternative assisted conception techniques 359
Oocyte donation 373
Embryo donation 385
Surrogacy 393
Regulation of embryo-endometrial interactions at implantation 405
Cryopreservation of human oocytes and ovarian tissue 421
In vitro maturation of oocytes 441
Preimplantation genetic diagnosis and its role in assisted reproduction technology 453
The role of sex selection techniques in an assisted reproductive technologies program 463
Recent scientific developments in assisted reproduction 475
Complications in assisted reproductive technology treatment 489
Quality management in reproductive medicine 501
Quality control in the in vitro fertilization laboratory 521
The health of children born after assisted reproductive technologies 529
New family forms 541
Nursing care in an assisted conception unit 557
Transport and satellite assisted reproductive technology 571
The distress of infertility : some thoughts after 22 years of infertility counseling 579
Ethical aspects of assisted conception and the law 589
The role of meta-analysis in clinical decision-making to optimize outcome 599
The application of medical informatics to reproductive medicine 609
Regulation of assisted reproductive technology : the UK experience - themes and trends 623
Regulation of assisted reproductive technologies : the Australian experience 633
Regulation of assisted conception treatment : Germany 641
Legislation and regulation of assisted reproductive technology in the Nordic countries 647
Regulating in vitro fertilization - the risks of over-regulation : Italy 655
Regulation of assisted reproductive technology : the USA experience 661
Regulation of assisted reproductive technology : the French experience 667