Assisted Reproductive Technologies Quality and Safety

Table of Contents
List of principal contributors
Preface
1 Assisted reproductive technologies: current achievements and
challenges for the future 1
2 Epidemiology of multiple pregnancy including natural versus
iatrogenic multiple pregnancy 9
3 Obstetric risks and neonatal complications of twin pregnancy
and higher-order multiple pregnancy 23
4 Prevention of multiple pregnancies after non-in vitro
fertilization treatment 39
5 Patient selection for single-embryo transfer 49
6 Embryo selection for elective single-embryo transfer 63
7 Impact of elective single-embryo transfer on the total and
multiple pregnancy rate 81
8 Elective single-embryo transfer in the first cycle of in vitro
fertilization/intracytoplasmic sperm injection 95
9 National experience with elective single-embryo transfer 105
Introduction 105
a Finland 106
b Belgium 113
c Sweden 119
d The Netherlands 123
10 Laboratory-related risks in assisted reproductive
technologies 127
11 Timing of embryo transfer as relevant to twin prevention 139
12 Epidemiology and pathophysiology of ovarian hyperstimulation
syndrome 149
13 Clinical management and therapy of ovarian hyperstimulation
syndrome 163
14 Ovarian hyperstimulation syndrome: prevention in IVF and non-
IVF treatment 169
15 Health-economic considerations regarding single- versus
double-embryo transfer 181
16 Oncogenic risks related to assisted reproductive technologies
187
17 Genetic considerations regarding azoospermic and severely
oligozoospermic men 201
18 Preimplantation genetic diagnosis: risks and complications
209
19 Preimplantation aneuploidy screening: myths and facts 223
20 Congenital anomalies after in vitro
fertilization/intracytoplasmic sperm injection 229
21 Miscellaneous risks and complications 247
22 Psychological complications of assisted reproductive
technologies 257
23 Philosophical and ethical considerations regarding assisted
reproductive technologies 267
Appendix 277
Index 281