Preface to the Series
Preface to the Volume
Contributors
Ch. 1 Perspectives in Neuroinjury and Disease 1
Ch. 2 Unique Aspects of Inflammation in the Central Nervous
System 21
Ch. 3 Parenchymal Cell Death and Leukocyte-Endothelial Cell
Interaction in Acute Experimental Inflammation 39
Ch. 4 Apoptosis in Neurodegenerative Diseases: New Therapeutic
Opportunities 53
Ch. 5 Constitutive Nitric Oxide Synthase and
Ischemic/Excitotoxic Brain Injury 85
Ch. 6 Osteopontin in Oxidative Stress Responses 97
Ch. 7 Inducible Nitric Oxide Synthase Gene Expression and
Ischemic Brain Damage 113
Ch. 8 Inflammatory Factors Regulating the Blood-Brain Barrier
137
Ch. 9 The Role of Superoxide Radicals in the Pathogenesis of
Cerebral Ischemic Cell Death 157
Ch. 10 Cytokine Expression in Brain Tumors: Its Role in Tumor
Biology and Tumor-associated Immune Responses 169
Ch. 11 The Inflammatory Mediator Platelet-Activating Factor and
the Inducible Prostaglandin Synthase (COX-2) Gene in CNS
Diseases 245
Ch. 12 Cytokines and Matrix Metalloproteinases in Inflammation
of the Blood-Brain Barrier 257
Ch. 13 Stroke Studies with Anti-Inflammatory Agents 267
Ch. 14 Complement in Brain Inflammation and Injury 283
Ch. 15 Gene Expression in Stroke 297
Ch. 16 Leukocyte Adhesion Molecules in the Treatment of Stroke
311
Ch. 17 Tumor Necrosis Factor [alpha] in Stroke and Neurotrauma
327
Ch. 18 Cytokine Mechanisms in Induced Brain Tolerance to Injury
349
Ch. 19 Kinins and CNS Injury and Inflammation: Effect of the
Bradykinin B[subscript 2] Antagonist, CP-0597, in Animal Models
of Stroke 361
Ch. 20 DNA Damage and Repair: An Alternative Mechanism of Cell
Death after Cerebral Ischemia 379
Ch. 21 Selections, ICAMs, and Integrins in CNS Injury 395
Ch. 22 Chemokines in Central Nervous System Inflammation 413
Ch. 23 The Expression and Function of Cell Adhesion Molecules in
Neurodegenerative Disease 437
Ch. 24 Cytokines in Acute Brain Injury and Stroke 471
Ch. 25 Inflammation-Mediated Neuronal Cell Injury 483
Ch. 26 Neurogenomics and the Discovery of Novel Inflammatory
Mediators in the Central Nervous System 497
Index 513