Clinical Pharmacology 9/e

This book is for students, doctors and indeed for all concerned
with evidence-based drug therapy. A knowledge of pharmacological
and therapeutic principles is essential if drugs/medicines are
to be used safely and effectively for increasingly informed and
critical patients.
Doctors who understand how drugs get into the body, how they
produce their effects, what happens to them in the body, and how
evidence of their therapeutic effect is assessed, will choose
drugs more skilfully, and use them more successfully than those
who do not. The principles involved are neither so numerous nor
so difficult to understand as to deter any prescriber, including
those whose primary interests lie elsewhere than in
pharmacology.

All who use drugs cannot escape either the moral or the
legal 'duty of care' to prescribe in an informed and responsible
way.





Section 1
General. Topics in drug therapy and clinical pharmacology.
Clinical pharmacology. Discovery and development of drugs.
Evaluation of drugs in man. Official regulation of medicines.
Classification of drugs: names of drugs.
Section 2
From Pharmacology to Toxicology. General pharmacology. Unwanted
effects of drugs: adverse reactions. Poisoning, drug overdose,
antidotes. Non-medical use of drugs.

Section 3
Inflammation, Immunology, Infection. Chemotherapy. Antibacterial
drugs. Chemotherapy of bacterial infections. Chemotherapy of
viral, fungal, protozoal and helminthis infections.
Inflammation, arthritis and non-steroidal anti-inflammatory
drugs (NSAIDs). Drugs and the skin.

Section 4
Nervous System. Pain and analgesics, drugs in palliative care,
narcotic analgesics. Sleep and hypnotics, anxiety and
anxiolytics. Drugs and mental disorder, psychotropics and
psychoactive drugs. Epilepsy, parkinsonism and allied
conditions. Anaesthesia and neuromuscular block.

Section 5
Cardiorespiratory and Renal Systems. Cholinergic (Cholomimetic)
and antimuscarinic (anticholinergic) drugs. Adrenergic
mechanisms, sympathomimetics, shock, hypotention. Drugs used in
arterial hypertension and angina. Cardiac dysrhythmia and
cardiac failure. Hyperlipidaemias. Kidney and urinary tracts.
Respiratory system.

Section 6
Blood and Neoplastic Disease. Drugs and haemostasis. Cellular
disorders and anaemias. Neoplastic disease and
immunosuppression.

Section 7
Gastrointestinal System. Stomach and oesophagus. Intestines.
Liver, biliary tract and pancreas. Section 8 Endocrine System,
Metabolic Conditions. Adrenal corticosteroids, antagonists,
corticotrophin. Diabetes mellitus, insulin, oral antidiabetic
agents. Thyroid hormones, antithyroid drugs. Hypothalmic and
pituitary hormones sex hormones, contraception, uterus.
Vitamins, calcium bone.