Neuromuscular Disorders of Infancy Childhood and Adolescence - A Clinician's Approach

I. Clinical and Laboratory Approach to the Infant and Child with
a Neuromuscular Problem 1. Introduction: Historical Perspectives
2. Genetics 3. EMG 4. Muscle Biopsy 5. Nerve Biopsy
II. Infantile Hypotonia and Arthrogryposis 6. Neonatal Hypotonia
7. Arthrogryposis
III. Anterior Horn Cell Disorders 8. Spinal Muscular Atrophies
9. Juvenile Muscular Atrophy of Unilateral Upper Extremity
(Hirayama Disease) 10. Juvenile ALS vs. Other Motor Neuron
Disorders 11. Infantile Poliomyelitis and Other Enteropathic
Motor Neuron Diseases
IV. Radiculopathies and Plexopathies 12. Radiculopathies 13.
Plexopathies Rabies
Peripheral Nerve Disorders 14. Vaccine Associated Poliomyelitis
15. Tetanus 16. Rabies
Mononeuropathies 17. Facial Palsies: Congenital and acquired 18.
Upper Extremities 19. Lower Extremities
Polyneuropathies 20. Overview of the Neuropathies 21. Congenital
and Early Infantile Neuropathies 22. Hereditary Charcot ?
Marie ?Tooth and Other Genetic Neuropathies 23. Guillain ?
Barre Syndrome 24. Acute Moter Axonal Neuropathy in Childhood
25. Tick Paralysis 26. Chronic Inflammatory Demyelinating and
Recurrent Neuropathies 27. Peripheral Neuropathy in Inherited
Metabolic Disease 28. Neuropathies Secondary to Systemic
Disorders 29. Childhood Hansen뭩 Disease 30. Toxic Neuropathies
31. Autonomic Neuropathies
V. Neuromuscular Junction Disorders 32. Infantile Botulism 33.
Congential Miyasthenia Gravis 34. Acquired Miyasthenia Gravis in
Childhood
VI. Myopathies 35. Clinical Syndromes of Congenital Myopathies
36. Congenital Muscular Dystrophies 37. Dystrophinopathies 38.
Facioscapulohumeral Dystrophy, Scapuloperoneal Syndromes and
Distal Myopathies 39. The Limb Girdle Muscular Dystrophies 40.
Emery ?Dreifuss Muscular Dystrophy 41. Myopathies of Systemic
Disease 42. Channelopathies Affecting Skeletal Muscle in
Childhood 43. Glycogen Storage Diseases of Muscle 44. Lipid
Storage Muscular Disorders 45. Myoadenylate Deaminase Deficiency
46. Metabolic : Mitochondrial 47. Juvenile Dermatomyositis and
other Inflammatory Myopathies in Children 48. Other Inflammatory
Myopathies: Viral Trichinosis, and Pyomyositis 49. Rigid Spine
Syndromes
VII. Special Clinical Problems 50. Neuromuscular Problems of the
Critically III Neonate and Child 51. HyperCKemia and
Rhabdomyolysis 52. Malignant Hyperthermia 53. Continuous Muscle
Fiber Activity Including the Stiff Person 54. Disorder of the
Ocular Motor Cranial Nerves and Extraocular Muscles 55.
Neurogenic Dysphagia in Newborns and Infants 56. Friedreich뭩
Ataxis, Vitamin E. Deficiency 57. Dominantly Inherited
Spinocerebellar Syndromes 58. Reflex Sympathetic Dystrophy
VIII. General Therapeutic Principles 59. Autoimmune
Pharmacotherapeutic Intervention in Children 60. Androgen and
Corticosteroid Therapy of Muscular Dystrophies: New Therapeutic
Modalities 61. The Principles and Practice of Molecular
Therapies 62. Intensive Care Management 63. Orthopedic Treatment
64. Rehabilitation of the Pediatric Patient with a Neuromuscular
Disease 65. Bioethical Issues



Author Information
By H. Royden Jones, Jr., MD, Clinical Professor of Neurology,
Harvard Medical School, Boston, MA; Jaime Ortiz-Patino Chair of
Neurology, Lahey Hitchcock Medical Center, Burlington, MA;
Director of EMG Laboratory, Children's Hospital, Boston, MA;
Darryl C. De Vivo, MD; and Basil T. Darras, MD, Associate
Professor of Neurology, Harvard Medical School, Boston, MA;
Director of Muscular Dystrophy Clinic, Children's Hospital,
Boston, MA.