Includes a brand-new section on Psychiatric Diseases, edited by
Dr. Eric J. Nestler, that features chapters on Challenges in
Psychiatric Genetics Depression Bipolar Disorders Schizophrenia
Obsessive-Compulsive Disorder and Tourette's Syndrome Molecular
and Genetic Basis of Addiction and Autism.
Offers two new chapters on Degenerative Diseases and Protein
Processing and Prion Diseases, authored by Dr. Stanley B.
Prusiner, winner of the 1997 Nobel Prize in Medicine for his
research defining the molecular and genetic basis of the
spongiform encephalopathies and the expression of the prion gene
under both physiologic and pathologic conditions.
Incorporates new data and insights from the analysis and
sequencing of the human genome into three new chapters on The
Human Genome Project and Neurological Disease, Gene Therapy, and
Ethical Issues in Diagnosis and Therapy.
Features 21 additional new chapters: Animal Models (mice, worms,
flies) Gene Targeting/Gene Mapping Genotype/Phenotype
Correlations Mitochondrial Disorders Due to Mutations in the
Nuclear Genome Mitochondria in Neurodegenerative Disorders
Lysosomal Membrane Disorders - LAMP-2 Deficiency Alzheimer's
Disease and Related Dementias Movement Disorders Neuronopathies
Limb Girdle Muscular Dystrophies Congenital Myopathies
Hereditary Inclusion - Body Myopathies Facioscapulohumeral
Muscular Dystrophy The Phakomatoses: Disorders of Skin and Brain
Disorder of Galactose Metabolism Disorders of Glucose Transport
Congenital Disorders of Glycosylation Disorders of Glutathione
Metabolism Friedreich Ataxia and Iron Metabolism The Influence
of Alpha Tocopherol, Caloric Restriction and Genes on Life Span
and A Neurologic Gene Map.