Diagnostic and Therapeutic Advances in Pediatric Oncology

Diagnostic and Therapeutic Advances in Pediatric Oncology, Vol. 92

TABLE OF CONTENTS
Contributors
Preface
I Understanding the Causes of Tumors of Childhood 1
1 Embryonic Development and Pediatric Oncogenesis 3
2 Immunodeficiency States and Related Malignancies 39
3 Familial Cancer Syndromes and Genetic Counseling 63
II Embryonal Tumors 99
4 Molecular Basis of Wilms' Tumor 101
5 Neuroblastoma: Solving a Biologic Puzzle 125
6 Pediatric Germ Cell Tumors 163
7 Hepatic Malignancies in Childhood and Adolescence (Hepatoblastoma,
Hepatocellular Carcinoma, and Embryonal Sarcoma) 201
III Sarcomas 213
8 Osteosarcoma 215
9 The Ewing's Sarcoma Family of Tumors: Ewing's Sarcoma and Peripheral
Primitive Neuroectodermal Tumor of Bone and Soft Tissue 253
10 Rhabdomyosarcoma: Biology and Therapy 309
IV Late Effects of Childhood Cancer 341
11 Late Effects of Cancer Therapy 343
Index 377