Table of Contents
Preface
List of contributors
1 Important issues in the design, analysis and interpretation of
clinical trials in neurology 1
Degenerative diseases of the nervous system 35
2 Alzheimer`s disease and other degenerative dementias 36
3 Disorders of the basal ganglia 59
4 Motor neurone disease 89
5 Management of cervical spondylotic radiculopathy and
myelopathy 114
Inflammatory diseases 129
6 Multiple sclerosis 130
7 Inflammatory peripheral nerve disease 147
8 Disorders of the neuromuscular junction 158
9 Inflammatory muscle disease 170
10 Neurological involvement in systemic autoimmune and
inflammatory diseases 187
11 Neurological infections 216
Acquired and inherited metabolic disease 235
12 Diabetic peripheral nerve disease 236
13 Inherited metabolic storage disease 249
14 Muscular dystrophies 264
15 Mitochondrial diseases 283
Vascular diseases of the central nervous system 303
16 Stroke prevention 304
17 Acute stroke treatments 329
Episodic neurological disease 355
18 The treatment of epilepsy 356
19 Headache 378
20 The genetic neurological channelopathies 398
Index