Table of Contents
Sect. I Effect on the Female Reproductive System
1 Nontraditional Sites of Endocrine Disruption by Chemicals on
the Hypothalamus-Pituitary-Gonadal Axis: Interactions with
Steroid Membrane Receptors, Monoaminergic Pathways, and Signal
Transduction Systems 3
2 Diethylstilbestrol (DES) and Environmental Estrogens Influence
the Developing Female Reproductive System 39
3 Ovotoxic Environmental Chemicals: Indirect Endocrine
Disruptors 57
4 Dietary Phytoestrogens 89
5 Estrogens, Xenoestrogens, and the Development of Neoplasms 125
6 Differential Regulation of Gene Expression by Estrogenic
Ligands: A Potential Basis for the Toxicity of Environmental
Estrogens 165
7 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Related
Environmental Antiestrogens: Characterization and Mechanism of
Action 187
Sect. II Effect on the Male Reproductive System
8 Endocrine Disruptors and Male Infertility 225
9 Environmental Antiandrogens as Endocrine Disruptors 247
10 Endocrine Disruptors and Sexual Dysfunction 279
11 The Role of Natural and Manmade Estrogens in Prostate
Development 307
12 Metal Ions and Prostate Cancer 329
Index