Cancer and Pregnancy

Table of Contents
1 The Epidemiology of Cancer in Pregnancy 1
2 Placental and Fetal Cancers 6
3 Breast Cancer and Pregnancy 21
4 Gynaecologic Malignancies in Pregnancy 33
5 Hematologic Malignancies in Pregnancy 50
6 Melanoma in Pregnancy 54
7 Rare Tumours in Pregnancy 69
8 Colorectal Cancer in Pregnancy 76
9 Radiologic Diagnosis of Cancer in Pregnancy 81
10 Pregnancy Derived Tumor Marker 93
11 Chemo and Radiation Therapy During Pregnancy 108
12 Management of Cancer in Pregnancy (Case Reports) 119
13 Transplacental Carcinogenesis: Role of Chemicals, Radiation
and Viruses 131
14 Metabolism of Chemotherapeutic Drugs by Maternal and
Conceptus Tissues 149
15 Adverse Reproductive Outcome Potential of Cancer Therapies
During Pregnancy 174
16 Immunomodulatory Analogies Between Trophoblastic and Cancer
Cells and Their Hosts 190
17 Protective Role of Human Chorionic Gonadotrophin and
Luteinizing Hormone Against Breast Cancer 209
18 Proliferation, Differentiation and Apoptosis in Pregnancy and
Cancer 216
19 Controlled vs Uncontrolled Angiogenesis: Color Doppler
Studies 229
20 Angiogenesis and Vasculogenesis in Pregnancy and in Tumor
Development 251
21 Trophoblast Implantation Versus Tumor Invasion 267
22 Pregnancy Derived Compounds that Control Proliferation 277
23 Cancer and Pregnancy: Bioethical and Legal Dilemmas 287
Epilogue: Cancer and Pregnancy: a Reason for Hope 298
Index 303