Asthma 2vols-1판

Foreword
Roland H. Ingram, Jr.
A. Introduction
1. Overview
Editors
2. History of asthma
Roger Ellul-Micalef
3. Definitions and clinical classification
Ann J. Woolcock
B. Epidemiology
4. Epidemiological trends
Peter Burney
5. Asthma deaths
Julian Crane, Neil Pearce, Carl Burgess, Richard Beasley
6. Ethnic differences
C.M. Salome and Ann J. Woolcock
7. Risk factors: IgE and atopy
Malcolm R. Sears
8. Indoor allergens as a risk factor for asthma
Adnan Custovic and Martin Chapman
9. Risk factors: diet
Scott T. Weiss
10. Risk factors: development and natural history
Fernando D. Martinez
11. Genetics of atopy
Carole L. Ober
12. Genetics of asthma
Djerke Postma
C. Structure, Biology and Pathology
13. Upper airways
Hemalini Mehta and William W. Busse
14. Normal airway structure
Manuel G. Cosio and Marina Saetta
15. Development of airways
Charles G. Plopper, Reed Wu, Michelle M. Voit, Judith A. St.
George
16. Postmortem pathology
James C. Hogg and Richard C. Hegele
17. Bronchial biopsies
Annika Laitinen, Lauri A. Laitinen, and Ismo Virtanen
18. Bronchoalveolar lavage studies
Mark C. Liu
19. Inflammation: basic concepts
Peter A. Ward
20. IgE
Donata A. Vercelli
21. Animal models
Debra J. turner and James G. Martin
22. Animal models for studying genetics of asthma
Roman A. Pauwels, Guy F. Joos, and Johan C. Kips
23. Receptor mechanisms
Peter J. Barnes and Michael M. Grunstein
24. Molecular and genetic basis of b-Adrenergic receptor
function and regulation
Stephen B. Liggett
25. Intracellular signalling mechanisms: the second messengers
David A. Bass
26. Transcription factors
Ian M. Adcock and Peter J. Barnes
D. Inflammatory Cells
27. Mast cell involvement in asthma
Yuji Shimizu and Lawrence B. Schwartz
28. Basophils
John T. Schroeder and Lawrence M. Lichtenstein
29. Macrophages
Galen B. Toews
30. Eosinophils
Mary E. Strek and Alan R. Leff
31. Neutrophils
Leonardo Fabbri, G. Caramori, M. Piattella and P. Mastrelli
32. T Lymphocytes in asthma pathogenesis
C.J. Corrigan and A. Barry Kay
33. Dendritic cell population
Patrick G. Holt
34. Platelets
Clive P. Page
35. Interstitial and bronchial fibroblasts
Patricia J. Sime, Guy Tremblay, Zhou Xing, Bengt Sarnstrand,
Jack Gauldie
36. Epithelial cells as inflammatory cells
Albert J. Polito and David Proud
37. The role of endothelial cells in asthma
Philippe Gosset, Pascale Jeannin, Philippe Lassalle, MNichel
Joseph and Andre-Bernard Tonnel
38. Cell adhesion molecules
Joseph M. Pilewski and Steven M. Albelda
E. Inflammatory Mediators
39. Histamine
MaryBeth Hogan and Paul A. Greenberger
40. Leukotrienes
Andrew R. Fisher and Jeffrey M. Drazen
41. Cyclooxygenase products
Paul M. O'Byrne
42. Platelet-activating factors and its implications
Paula L. Watson and James R. Snapper
43. Bradykinin
Peter J. Barnes
44. Adenosine
Diana L. Marquardt
45. Eosinophil basic proteins
Masayuki Kaneko, Hirohito Kita, Gerald J. Gleich
46. Proteases
George Caughey and Jay A. Nadel
47. Reactive oxygen species
William M. Abraham
48. Complement fragments
Norma P. Gerard
49. Proinflammatory cytokines
Johan C. Kips and Romain A. Pauwels
50. Lymphokines
Kaiser G. Lim and Peter F. Weller
51. Chemokines
Kian Fan Chung
52. Growth factors
Jason Kelley
53. Nitric oxide
Richard A. Robbins
54. Endothelins
Douglas W.P. Hay and Roy G. Goldie
F. Target Cells
55. Airway smooth muscle structure
Richard W. Mitchell and Andrew J. Halayko
56. Airway smooth muscle contraction
Newman L. Stephens, Jizhong Wang and Andrew J. Halayko
57. Molecular biology of potassium channels in airway smooth
muscle
Michael I. Kotlikoff
58. Airway smooth muscle in asthma
Judith L. Black
59. Airway smooth muscle hyperplasia and hypertrophy
Reynold A. Panettieri, Jr. and Michael M. Grunstein
60. Airway mucus secretion
James H. Shelhamer
61. Mucociliary clearance
Adam Wanner
62. Epithelium-dependent responsiveness of airway smooth