[보안 로그인 하기]
[회원가입]  [ID/PW찾기]
대한민국 원환율 (2021-08-27)
통화 금액
USD 1,170
EUR 1,377
GBP 1,603
JPY 1,065
CAD 925
Fetal and Neonatal Physiology-6판 2Vols
Fetal and Neonatal Physio
       판매가 : 455,000400,000
       적립금 : 8,000
       저   자 : Richard A. Polin
       역   자 :
       출판사 : Elsevier
    ISBN(13) : 9780323712842
       발행일 : 2021-07-29  /   6판   /   2040 페이지
       상품코드 : 28633
       수 량 :
       

Description


Offering the comprehensive authoritative information needed for effective diagnosis treatment and management of sick and
premature infants Fetal and Neonatal Physiology 6th Edition is an invaluable resource for board review clinical rounds
scientific research and day-to-day practice. This trusted two-volume text synthesizes recent advances in the field into
definitive guidance for today’s busy practitioner focusing on the basic science needed for exam preparation and key
information required for full-time practice. It stands alone as the most complete text available in this complex and fast-
changing field yet is easy to use for everyday application.

Key Features

  • Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants.

  • Contains new chapters on Pathophysiology of Genetic Neonatal Disease, Genetic Variants and Neonatal Disease, and
    Developmental Biology of Lung Stem Cells, as well as significantly revised chapters on Cellular Mechanisms of Neonatal
    Brain Injury, Neuroprotective Therapeutic Hypothermia, Enteric Nervous System Development and Gastrointestinal Motility, and
    Physiology of Twin-Twin Transfusion.
  • Features 1,000 full-color diagrams, graphs and anatomic illustrations, 170+ chapters, and more than 350 global
    contributors.

  • Includes chapters devoted to clinical correlation that help explain the implications of fetal and neonatal physiology,
    as well as clinical applications boxes throughout.

  • Provides summary boxes at the end of each chapter and extensive cross-referencing between chapters for quick reference
    and review.

  • Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging,
    and much more.

  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and
    references from the book on a variety of devices.

    Contents


    Volume 1

    Section I Genetics and Embryology

    1 Basic Genetic Principles, 1
    2 Epigenetics, 11
    3 Basic Embryology, 23
    4 Regulation of Embryogenesis, 38
    5 The Extracellular Matrix in Development, 47
    6 Angiogenesis, 54
    7 Prenatal Diagnosis, 58

    Section II Placenta and

    8 Placental Development, 67
    9 Regulation of the Placental Circulation, 80
    10 Mechanisms of Transfer Across the Human Placenta, 89
    11 Endocrine and Paracrine Function of the Human Placenta, 101
    12 Intra-Amniotic Infection/Inflammation and the Fetal Inflammatory Response Syndrome, 111
    13 Fetal Origins of Adult Disease: A Classic Hypothesis With New Relevance, 129
    14 Placental Function in Intrauterine Growth Restriction, 137
    15 Basic Pharmacologic Principles, 150
    16 Principles of Pharmacokinetics, 166
    17 The Physiology of Placental Drug Disposition, 173
    18 Pharmacogenomics, 187
    19 Drug Distribution in Fetal Life, 194
    20 Drug Transfer During Breastfeeding, 203
    21 Placental and Fetal Circulatory and Metabolic Changes Accompanying Fetal Growth Restriction, 214
    22 Endocrine Factors Affecting Neonatal Growth, 224
    23 Human Milk Composition and Function in the Infant, 241
    24 Physiology of Lactation, 249
    25 Fetal and Neonatal Iron Metabolism, 257
    26 Fetal and Neonatal Calcium, Phosphorus, and Magnesium Homeostasis, 265
    27 Zinc in the Fetus and Neonate, 282
    28 Vitamin A Metabolism in the Fetus and Neonate, 287
    29 Vitamin E Nutrition in Pregnancy and the Newborn Infant, 295
    30 Vitamin K Metabolism in the Fetus and Neonate, 303

    Section VI Lipid Metabolism

    31 Maternal-Fetal Transfer of Lipid Metabolites, 311
    32 Brown Adipose Tissue: Development and Function, 323
    33 Lipids as an Energy Source for the Premature and Term Neonate, 332
    34 Ketone Body Metabolism in the Neonate, 339
    35 Long-Chain Polyunsaturated Fatty Acids in Neurodevelopment, 348
    36 Glucose Metabolism in the Fetus and Newborn, and Methods for Its Investigation, 358
    37 Oxygen Consumption and General Carbohydrate Metabolism of the Fetus, 368
    38 Role of Glucoregulatory Hormones in Hepatic Glucose Metabolism During the Perinatal Period, 382
    39 Cell Glucose Transport and Glucose Handling During Fetal and Neonatal Development, 392
    40 General Concepts of Protein Metabolism, 400
    41 Placental Transfer and Fetal Requirements of Amino Acids, 408

    Section IX View less > Thermoregulation

    42 Temperature Control in Newborn Infants, 423

    Section X Skin

    43 Structure and Development of the Skin and Cutaneous Appendages, 446
    44 Physiologic Development of the Skin, 454

    Section XI Fetal and Neonatal Cardiovascular Physiology

    45 Cardiovascular Development, 473
    46 Developmental Electrophysiology in the Fetus and Neonate, 482
    47 Developmental Biology of the Pulmonary Vasculature, 501
    48 Development of the Gastrointestinal Circulation in the Fetus and Newborn, 517
    49 Physiology of Congenital Heart Disease in the Neonate, 521
    50 Regulation of Cardiovascular Function During Fetal and Newborn Life, 534
    51 Nutritional and Environmental Effects on the Fetal Circulation, 545
    52 Mechanisms Regulating Closure of the Ductus Arteriosus, 553
    53 Umbilical Circulation, 564
    54 Fetal and Placental Circulation During Labor, 576

    Section XII The Lung

    55 Normal and Abnormal Structural Development of the Lung, 585
    56 Regulation of Alveolarization, 600
    57 Physiologic Mechanisms of Normal and Altered Lung Growth Before and After Birth, 605
    58 Molecular Mechanisms of Lung Development and Lung Branching Morphogenesis, 617
    59 Regulation of Liquid Secretion and Absorption by the Fetal and Neonatal Lung, 626
    60 Upper Airway Structure: Function, Regulation, and Development, 635
    61 Regulation of Lower Airway Function, 645
    62 Functional Development of Respiratory Muscles, 652
    63 Mechanics of Breathing, 665
    64 Pulmonary Gas Exchange in the Developing Lung, 673
    65 Oxygen Transport and Delivery, 684
    66 Control of Breathing in Fetal Life and Onset and Control of Breathing in the Neonate, 697
    67 Basic Mechanisms of Oxygen Sensing and Adaptation to Hypoxia, 707
    68 Evaluation of Pulmonary Function in the Neonate, 714
    69 Mechanisms of Neonatal Lung Injury, 728
    70 Impaired Lung Growth After Injury in Preterm Lung, 734
    71 Antenatal Factors That Influence Postnatal Lung Development and Injury, 748
    72 Regulation of Pulmonary Circulation, 757

    SECTION XIII Surfactant

    73 Historical Perspective, 765
    74 Developmental Biology of Lung Stem Cells, 768
    75 Surfactant Homeostasis: Composition and Function of Pulmonary Surfactant Lipids and Proteins, 776
    76 Structure and Development of Alveolar Epithelial Cells, 787
    77 Regulation of Surfactant-Associated Phospholipid Synthesis and Secretion, 792
    78 Antenatal Hormonal Therapy for Prevention of Respiratory Distress Syndrome, 804
    79 Surfactant Treatment, 813
    80 Genetics and Physiology of Surfactant Protein Deficiencies, 825

    SECTION XIV Physiology of Gastrointestinal Tract in the Fetus and Neonate

    81 Trophic Factors and Regulation of Gastrointestinal Tract and Liver Development, 838
    82 Organogenesis of the Gastrointestinal Tract, 845
    83 Development of Gastric Secretory Function, 854
    84 Development of the Enteric Nervous System and Gastrointestinal Motility, 859
    85 Development of the Endocrine and Exocrine Pancreas, 868
    86 Digestive-Absorptive Functions in Fetuses, Infants, and Children, 881
    87 The Developing Microbiome of the Fetus and Neonate: A Multiomic Approach, 888

    SECTION XV Liver and Bilirubin Metabolism

    88 Organogenesis and Histologic Development of the Liver, 896
    89 Bile Acid Metabolism During Development, 901
    90 Fetal and Neonatal Bilirubin Metabolism, 915
    91 Hereditary Contributions to Neonatal Hyperbilirubinemia, 919
    92 Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia, 930

    Volume 2

    Section XVI The Kidney

    93 Development of the Kidney: Morphology and Mechanisms, 941
    94 Functional Development of the Kidney in Utero, 954
    95 Development and Regulation of Renal Blood Flow in the Neonate, 965
    96 Postnatal Development of Glomerular Filtration Rate in Neonates, 975
    97 Renal Transport of Sodium During Development, 984
    98 Potassium Homeostasis in the Fetus and Neonate, 992
    99 Role of the Kidney in Calcium and Phosphorus Homeostasis, 1006
    100 Transport of Amino Acids in the Fetus and Neonate, 1018
    101 Organic Anion Transport in the Developing Kidney, 1024
    102 Concentration and Dilution of Urine, 1030
    103 Urinary Acidification, 1047
    104 Response to Nephron Loss in Early Development, 1056

    SECTION XVII Fluid and Electrolyte Metabolism

    105 Fluid Distribution in the Fetus and Neonate, 1064
    106 Regulation of Acid-Base Balance in the Fetus and Neonate, 1076
    107 Developmental Biology of Hematopoietic Stem Cells, 1082
    108 Neutrophil Granulopoiesis and Homeostasis, 1093
    109 Developmental Erythropoiesis, 1104
    110 Developmental Megakaryopoiesis, 1125

    Section XIX Hemostasis

    111 Developmental Hemostasis, 1145
    112 Platelet쭯Vessel Wall Interactions, 1153
    113 Host Defense Mechanisms Against Bacteria, 1158
    114 Host Defense Mechanisms Against Fungi, 1167
    115 Host Defense Mechanisms Against Viruses, 1172
    116 T-Cell Development, 1195
    117 B-Cell Development, 1200
    118 Mononuclear Phagocyte System, 1206
    119 Normal and Abnormal Neutrophil Physiology in the Newborn, 1215
    120 The Complement System of the Fetus and Newborn, 1232
    121 Cytokines and Inflammatory Response in the Fetus and Neonate, 1243
    122 Immunology of Human Milk, 1257
    123 Neonatal Pulmonary Host Defense, 1265

    Section XXI Neurology

    124 Development of the Nervous System, 1297
    125 Mechanisms of Cell Death in the Developing Brain, 1318
    126 Development of the Blood-Brain Barrier, 1327
    127 Trophic Factor, Nutritional, and Hormonal Regulation of Brain Development, 1341
    128 Developmental Aspects of Pain, 1347
    129 Cerebellar Development―The Impact of Preterm Birth and Comorbidities, 1353
    130 Electroencephalography in the Preterm and Term Infant, 1367
    131 Intraventricular Hemorrhage in the Neonate, 1394
    132 Pathophysiology of Neonatal White Matter Injury, 1414
    133 Cellular and Molecular Mechanisms of Neonatal Brain Injury and Neuroprotection, 1422
    134 Neuroprotective Therapeutic Hypothermia, 1432

    Section XXII Special Sensory Systems in the Fetus and Neonate

    135 Early Development of the Human Auditory System, 1440
    136 Development of Olfaction and Taste in the Human Fetus and Neonate, 1455

    Section XXIII  Musculoskeletal

    137 The Growth Plate: Embryologic Origin, Structure, and Function, 1465
    138 Ontogenesis of Striated Muscle, 1475

    Section XXIV Endocrine Function

    139 Hypothalamus: Neuroendometabolic Center, 1495
    140 Growth Factor Regulation of Fetal Growth, 1505
    141 Growth Hormone, Prolactin, and Placental Lactogen in the Fetus and Newborn, 1514
    142 Luteinizing Hormone and Follicle-Stimulating Hormone Secretion in the Fetus and Newborn Infant, 1520
    143 Development of the Hypothalamus-Pituitary-Adrenal Axis in the Fetus, 1532
    144 Fetal and Neonatal Adrenocortical Physiology, 1538
    145 Fetal and Neonatal Thyroid Physiology, 1546

    Section XXV Ovary and Testis

    146 Genetics of Sex Determination and Differentiation, 1555
    147 Differentiation of the Ovary, 1566
    148 Testicular Development and Descent, 1574

    Section XXVi View less > PAT HOPHYSIOLOGY OF NEONATAL DISEASES

    149 The Pathophysiology of Twin-Twin Transfusion Syndrome,
    Twin-Anemia Polycythemia Sequence, and Twin-Reversed Arterial Perfusion, 1582
    150 Physiology of Neonatal Resuscitation, 1589
    151 Pathophysiology of Neonatal Sepsis, 1606
    152 Pathophysiology of Neonatal Hypoglycemia, 1624
    153 Pathophysiology of Cardiomyopathies, 1633
    154 Pathophysiology of Persistent Pulmonary Hypertension of the Newborn, 1648
    155 Pathophysiology of Shock in the Fetus and Neonate, 1662
    156 Pathophysiology of Apnea of Prematurity, 1671
    157 Pathophysiology of Respiratory Distress Syndrome, 1680
    158 Pathophysiology of Meconium Aspiration Syndrome, 1696
    159 Pathophysiology of Bronchopulmonary Dysplasia, 1703
    160 Pathophysiology of Ventilator-Dependent Infants, 1710
    161 Pathophysiology of Gastroesophageal Reflux, 1722
    162 Pathophysiology and Prevention of Neonatal Necrotizing Enterocolitis, 1732
    163 Pathophysiology of Kernicterus, 1738
    164 Pathophysiology of Neonatal Acute Kidney Injury, 1750
    165 Pathophysiology of Edema, 1760
    166 Pathophysiology of Retinopathy of Prematurity, 1765
    167 Pathophysiology of Neonatal Hypoxic-Ischemic Brain Injury, 1773
    168 Pathophysiology of Neonatal Acute Bacterial Meningitis, 1784
    169 Pathophysiology of Neural Tube Defects, 1797
    170 Pathophysiology of Preeclampsia, 1811
    171 Pathophysiology of Preterm Birth, 1820
    172 Pathophysiology of Chorioamnionitis: Host Immunity and Microbial Virulence, 1828
    173 Pathophysiology of Genetic Neonatal Disease, 1837
    174 Genetic Variants and Neonatal Disease, 1846
  • 클릭 하시면 에스크로 가입여부를 확인 하실 수 있습니다.