Male sexual dysfunction (MSD) encompasses a variety of conditions that impair sexual function in men.
It may occur at any stage of the sexual response cycle—desire, arousal, or orgasm—and involves multifactorial etiologies.
This comprehensive volume provides an integrated understanding of MSD, covering its causes, diagnostic approaches, and evidence-based treatment options. It also highlights the psychological and emotional implications for affected men and
their partners.

While several books address male sexual dysfunction, most present fragmented topics or focus narrowly on specific
advances or pathophysiologic mechanisms.

In contrast, Diagnosis and Treatment of Male Sexual Dysfunction offers a unified framework combining foundational concepts, updated epidemiologic insights, modern diagnostic algorithms, and comparative analyses of therapeutic modalities
supported by efficacy and safety data.

This book addresses a broad spectrum of MSD, including erectile dysfunction, premature ejaculation, anhedonic orgasm,
priapism, and Peyronie’s disease. It also features a dedicated chapter on oncosexology, a field rarely explored
in standard MSD references.

Diagnosis and Treatment of Male Sexual Dysfunction serves as a definitive reference for clinicians, researchers,
and trainees seeking to understand and manage this prevalent and complex aspect of men’s health.


01 Introduction to Male Sexual Dysfunction (MSD) 1

02 Anatomy and Physiology of Male Sexual Dysfunction 11

03 Erectile Dysfunction: Epidemiology and Diagnosis 33

04 Advances in the Treatment of Erectile Dysfunction 49

05 Surgical Treatment of Erectile Dysfunction 67

06 Regenerative Therapies for Erectile Dysfunction: How Far Are We with the Evidence? 85

07 Advances in the Management of Peyronie’s Disease 121

08 Comprehensive Management of Premature Ejaculation 137

09 Post-Orgasmic Illness Syndrome: Systematic Review of the Literature 157

10 Anhedonia and Orgasmic Dysfunction 165

11 Epidemiology, Pathophysiology, and Diagnostic Approach of Priapism 171

12 Advances in the Treatment of Priapism 183

13 Management of Testosterone Deficiency Syndrome 197

14 Sexual Pain in Men 211

15 Oncosexology and Oncofertility in Men 223

Correction to: Post-Orgasmic Illness Syndrome: Systematic Review of the Literature C1

Index 237